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  • Situational Update
  • Acute Flaccid Myelitis (AFM)

Clinician Guidance for Acute Flaccid Myelitis (AFM)

As the winter season approaches, an increase in the circulation of respiratory pathogens, including enteroviruses, is expected. Enterovirus D-68 (EV-D68) is believed to be the main enterovirus responsible for the uncharacteristic increase in acute flaccid myelitis (AFM) cases observed during 2014, 2016, and 2018, which are referred to as peak years. Although there has been an increase in EV-D68 detections in the United States this year, the number of reported cases of AFM has remained relatively low, to date.  As of November 1, 2024, the Centers for Disease Control and Prevention (CDC) has received 26 reports of suspected AFM, with 15 confirmed cases in 11 states.  In past years, increases in EV-D68 respiratory disease have preceded cases of AFM by about 2 weeks. Therefore, vigilance for possible increases in EV-D68 respiratory disease and AFM is important.1 Click “Download PDF” for more information and clinical guidance.

  1. Centers for Disease Control and Prevention. Remaining Vigilant for AFM/polio, (September 18, 2024).